Benjamin Redelings

Benjamin Redelings
Research Scholar
Mathematical & Computational Biology
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I am a mathematical and computational biologist.  I use mathematics and computational techniques to answer questions in evolutionary genetics. The mathematics is mostly Bayesian inference and stochastic process modeling. The computation is primarily Markov chain Monte Carlo (MCMC). The evolutionary genetics is focused on inferring evolutionary trees and multiple sequence alignments, but also includes some coalescent theory.

After completing my PhD in Biomathematics at UCLA, I did postdoctoral work at North Carolina, the National Evolutionary Synthesis Center (NESCent).  Since then I've been working as a research scientist at the Duke University and the University of Kansas. I've worked on population genetics and the coalescent, and malaria genetics.  I'm currently working on the Open Tree of Life project with Mark Holder at the University of Kansas.

I also develop model-based methods for inferring multiple sequence alignments (MSA) that place insertions and deletions on specific branches of the evolutionary tree, instead of just placing gaps in a matrix. These methods also co-estimate the evolutionary tree along with the alignment. I develop the MCMC software BAli-Phy to perform this estimation.

To find out more, visit: http://ben-redelings.org/

You can contact me at benjamin.redelings@gmail.com

Some recent publications as of 2023:

  • (submitted) Redelings BD, Holder MT. Speeding up iterative applications of the BUILD supertree algorithm.
  • (submitted) Gartner V, Redelings BD, Gaither C, Parr JB, Kalonji FP, Brazeau NF, Juliano JJ, Wray GA.  Genomic insights into Plasmodium vivax population structure and diversity in central Africa.  [WWW]
  • (2022) Seo T. K, Redelings BD, Thorne JL (2022) Correlations between alignment gaps and nucleotide
    substitution or amino acid replacement. PNAS. [WWW]
  • (2021) Redelings BD. BAli-Phy version 3: model-based co-estimation of alignment and
    phylogeny, Bioinformatics, [WWW]
  • (2020) Brazeau NF, Mitchell CL, Morgan AP, Deutsch-Feldman M, Watson OJ, Thwai KL, Waltmann
    A, Emch M, Gartner V, Redelings BD, Wray G, Mwandagalirwa MK, Tshefu AK,
    Likwela JL, Edwards JK, Verity R, Parr JB, Meshnick SR, Juliano JJ. The
    epidemiology of Plasmodium vivax among adults in the Democratic Republic of the
    Congo. Nat Commun 12:4169. [WWW]
Bayesian Statistics, MCMC, Phylogenetics, Sequence alignment
Bioinformatics, Genetics, Mathematics, Population Genetics, Statistics