Faith Evelyn

Faith Evelyn   •   Lianne Abrahams
Research Scholar
Single Cell Systems Biology
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Hi, I'm Faith.

At present, I am ideating a collaborative plan to democratise the public communication of academic findings. Ordinarily, scholars publish their works in academic journals, in a language intended for a specialist audience. While this practice makes sense from an efficiency perspective, I think it could be augmented by publication of twin articles designed for a public audience. This would mean, in theory, that any and all individuals can intellectually access papers published in academic journals. Arguably, the twin language approach would be more socially inclusive, and invites the general public as partners. Given that almost all academic works are publicly funded, the approach would ensure that academics are held to account as servants of the public. The twin language initiative dovetails with Ronin values of openness, transparency, and participation, and I am intrigued to discover how fellow members and I will advance this idea.

Recently, since 2023, I have been developing an educational enterprise designed for the artificial intelligence (AI) era. As the fourth industrial revolution re-shapes the economy, the meaning and purpose of our lives will metamorphose. And as Founder of Won Moment, my aim is to offer to parents an online short course in home education, akin to a mini-PGCE. We will educate parents to flourish as natural and confident teachers, in synchronicity with their own child’s wonderment. This is an evolving work; half of the content has been created, and updates will be provided in due course.

In 2020-22, I was fixated mostly on the biology of Covid-19 and authored the acquired acute porphyria hypothesis. As part of my MSc in Bioinformatics, I conducted a systematic review and meta-analysis investigating the association between Covid-19 mortality and exposure to each of three different types of intervention. I found a significant association between antithrombotics exposure and reduction in relative risk of Covid-19 mortality, particularly for aspirin exposure.

My main scientific research interest is the philosophical reimagination of cancer biology. Systems level analysis explains the emergence of properties that effect cellular decision-making. Single cell approaches illuminate clinically relevant intercellular heterogeneity. Single cell-systems biology thus offers the best chance to reverse engineer the aetiology of cellular transformation and to untangle the evolution of chemotherapeutic resistance.

Perhaps the central problem in cancer biology is that we, too often, target expression rather than behaviour. I have considered a way to target behaviour: 6D phase portrait analysis. In the near future, I intend to learn machine and deep learning techniques, plus a method for converting protein activity data into subgraphs and 6D phase portraits. The 6D phase portraits will serve as substrates for image classification, to predict the chemo-resistance risk profile of single cells. This is an idea I developed in 2018-2020 and published in Bioinformatics the subsequent year.

Overall, I highly value the autonomy and creative licence fostered by Ronin culture.

To collaborate, contact: lianne.abrahams@protonmail.com

 

†My pen and birth name is Lianne Abrahams; my preferred name is Faith Evelyn. Thank you for your understanding.